Practical work of students

Task №1. To receive the model of Mountain sickness, to study its main symptoms (viewing of video film «Modeling of Mountain sickness»)

Technique. A mouse is placed in a hermetically sealed balloon of Komovsky’s apparatus. Examine an initial condition of an animal: behavior, character of breath, color of skin and mucous, with the help of the pump gradually pump out air, watching for a level of barometric pressure on a manometer. Fix character and sequence of changes at the level of barometric pressure 0.8 atm., 0.6 atm., 0.4 atm., 0.2 atm. In occurrence of convulsions immediately let air under the balloon. The received data bring in the table, conclude.

THE REPORT OF EXPERIMENT.

Questions
1. What factors affect the mouse in this experiment?

Which of these factors could be considered the leading cause of the pathologic process - hypobaric hypoxia?

How can you experimentally check your presumptions about the nature of the pathologic process?

Manometer reading of Komovsky’s apparatus in comparison with altitude above sea level and saturation of blood by oxygen

Task №2. To analyze Paul Bert’s experiment.

Two groups of mice are placed into the balloons of Komovsky’s apparatus. The first balloon is filled with air where barometric pressure is gradually reduced up to 210 mm. Hg. Thus animals have symptoms of Mountain sickness, convulsions develop.

The second balloon is filled with oxygen. Barometric pressure in this chamber is reduced up to 200 mm.Hg. Symptoms of Mountain sickness at animals of this group are absent. Which barocamera will have more alive mice? Why? Explain.

The task №3. Study the graphs of logic structure of Mountain sickness (High altitude disease)

№ 1.