2015-04-17
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Administration of drugs
The route of administration of a drug is very important in determining the rate and completeness of its absorption into the blood stream and speed and duration of the drug’s action in the body.
Oral Administration
The route of administration is by mouth. Drugs given orally must pass into the stomach and be absorbed into the blood stream through the intestinal wall. This method may have several disadvantages. If the drug is destroyed in the digestive tract by the digestive juice or if the drug cannot pass through the intestinal wall or mucosa, it will be ineffective.
Sublingual Administration
In this route of administration, drugs are not swallowed but are placed under the tongue and allowed to dissolve in the saliva. Absorption may be rapid for some agents. Nitroglycerine tablets are taken this way to treat attacks of chest pain.
Rectal Administration. Suppositories
Sometimes, drugs are given by rectum when oral administration presents difficulties such as, when the patient is nauseated and vomiting.
